Clinical Trials

At Chinook Therapeutics, we believe our work should be informed by patients and for patients. Our partnerships with leading Patient Advocacy Organizations enable us to better understand our patients and their needs. We’re also committed to improving patient access and representation in our clinical trials through financial assistance or compensation for out-of-pocket costs. We thank patients and their families for their interest in our clinical trials. Clinical trial participation makes our research and advances in the treatment of kidney disease possible.

If you have any questions about our clinical trials, please speak with your physician or contact clinicaltrials@chinooktx.com

Indication Program* Trial Number Trial Name
IgA Nephropathy (IgAN) Atrasentan​ NCT04573478 Phase 3 Study of Atrasentan in IgA Nephropathy (The ALIGN Study)
IgA Nephropathy (IgAN) Atrasentan​ NCT04573920 Phase 2 Basket Study of Atrasentan in Proteinuric Glomerular Disease (The AFFINITY Study)
IgA Nephropathy (IgAN) BION-1301 NCT03945318 A Phase 1, Multicenter Trial to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BION-1301 in Healthy Volunteers and Adults With IgA Nephropathy
Alport Syndrome Atrasentan NCT04573920 Phase 2 Basket Study of Atrasentan in Proteinuric Glomerular Disease (The AFFINITY Study)
Primary Focal Segmental Glomerulosclerosis (FSGS) Atrasentan NCT04573920 Phase 2 Basket Study of Atrasentan in Proteinuric Glomerular Disease (The AFFINITY Study)
Diabetic Kidney Disease Atrasentan NCT04573920 Phase 2 Basket Study of Atrasentan in Proteinuric Glomerular Disease (The AFFINITY Study)

*Our programs are investigational therapies. An investigational therapy is a drug that has not yet been approved by the FDA. Efficacy and safety have not been established, and there is no guarantee that it will become commercially available for the use(s) under investigation. Participation in one of our clinical trials is the most appropriate way to access our investigational therapies.

Patient Resources

The following is a list of resources for patients and families with reliable information related to kidney health and clinical trials.


ClinicalTrials.gov

ClinicalTrials.gov is a registry with information about the location of clinical trials, their design and purpose, and eligibility criteria. Search the database for Chinook trials or other clinical trials. www.clinicaltrials.gov


Center for Information and Research on Clinical Research Participation (CISCRP)

CISCRP is a nonprofit organization dedicated to educating and informing the public, patients, medical/research communities, the media, and policy makers about clinical research. www.ciscrp.org


American Association of Kidney Patients (AAKP)

AAKP is the oldest and largest, independent kidney patient organization in the U.S. dedicated to improving the lives and long-term outcome of kidney patients through education, advocacy, patient engagement and the fostering of patient communities. www.aakp.org

Advocacy Partners

The following is a list of our advocacy partners, that can provide patients and families with reliable information related to kidney health and clinical trials.

National Kidney Foundation logo

The NKF is a major non-profit health organization focused on awareness, education, prevention and treatment of kidney disease. www.kidney.org

NephCure logo

NephCure’s mission is to accelerate research for effective treatments for rare forms of Nephrotic Syndrome, and to provide education and support that will improve the lives of those affected by these protein-spilling kidney diseases. www.nephcure.org

IGA Nephropasthy logo

A patient-centric non-profit organization focused on finding a cure for IgA Nephropathy through funding research, using patient advocacy to empower patients, and building a network of support. www.igan.org

Alport Syndrome logo

Alport Syndrome Foundation is the leading independent non-profit organization in the United States educating and giving a voice to the Alport syndrome community through education, empowerment, advocacy and research. www.alportsyndrome.org

OHF logo

The Oxalosis & Hyperoxaluria Foundation (OHF) is dedicated to finding treatments and a cure for all forms of hyperoxaluria. www.ohf.org​